Are you planning on a fast blast to your destination or a slow meander on back country roads until you eventually get there?
I go overboard as I ride in Nevada where there are areas hours from help.
For navigation, I've done both planned and spontaneous. Planned rides I pre-study the route until I know it by heart, have little flash cards of the main stops/junctions, Google Maps on my phone for spot checking, and a little handheld GPS for tracking as I go. Wandering rides I end up knowing where I need to be in how ever many days and wing it day by day, using Google Maps to give me a rough route and my little GPS to spot check myself. Verizon has enough coverage in areas I would stop in that I never worried too much about not being able to get data signal. However, always carry a paper map, even if the generic state highway map.
For packing, my bike is basically a tank, so I only carried stuff I know would break/run out. Tire sticky string and air compressor, chain goop and pack jack thingy to adjust the chain, motor oil, spare headlight bulbs, bunch of batteries, beefed up tool kit for most minor repairs, SPOT Gen3, and about a half gallon of gas. I also carry a warm layer (warm gloves, heated jacket with maybe a fleece jacket, little fleece hat) if I get stuck at nights (especially summer when I go from 100+ heat to 70+ nights), gets cold - especially if you run out of gas at night. For unexpected hotel stays, I keep a TSA sized toiletry kit with a slim power strip and enough wires for my gizmos.
Clothes, I wore my LDComforts only under my gear during the day and washed them in the hotel shower/sink at night. Always hung my gear up to let it air out while I wore really light sleepwear. That left me down to only a change or two of real clothes needed for the few days I hung out with other people.
Here's my gear for a two week meander ard the West Coast. Tank bag held daily snacks and quick grab items like camera and phone when the summer heat baked it. Front side bags held camping meals and cookware. Tailbag holds the stuff listed above. Saddlebags held tie down straps and other recovery items, with spare clothes in the other. And you can see the sleepstuff strapped where it fit.
Like I said, overboard.